Keywords : Oxidative stress
Mosul Journal of Nursing,
Volume 6, Issue 1, Pages 14-19
Background: There is a relationship between oxidative stress and rheumatoid arthritis.
Objective: to assess total antioxidant status by measurement of total antioxidants status, and oxidative stress by measurement malondialdehyde, in patients with.
Design: case -control study.
Setting: referred patients from private clinics .
Methodology: The study was conducted on patients referred from private clinics of rheumatology. The period between Nov.1st 2017 and Jun. 1st 2008. thirty four female with rheumatoid Arthritis , and thirty, sex and age-matched healthy volunteers as control group participated in the study. Total antioxidants status and malondialdehyde were measured in both groups.
Results: rheumatoid Arthritis patients have lower total antioxidants status values than that of the control group (0.94±0.24 and 1.95±0.20 respectively) (P value <0.0001). The malondialdehyde values was higher in patients group than control group (1.34±0.42 and 0.88±0.26 respectively) (P value <0.0001).
Conclusion: rheumatoid Arthritis patients have decreased level of total antioxidants status and increased level of malondialdehyde than the control group .